Clair Is Not A Match
I got the news yesterday that Clair is not a match. Every person has 6 Antigens. You get 3 from your mom and 3 from your dad. The three antigens I received from my mom are not the same three antigens my sister received from my mom.
Since I received a transplant from my mom, my body developed antibodies to the 3 antigens of hers that I wasn't born with, the three antigens that Clair got when she was born. So, not only are we not a match, but my blood reacts to hers based on the antibodies I have developed.
Heather is getting tested now, the odds that we are a 6 out of 6 antigen match are the same (roughly 25%), but since I just came up Snake Eyes on Clair, I'm feelin' lucky.
Separately, I talked with Dr. Howard (Nephrologist) this week. He just completed reviewing the 2 year data on Belatacept and he's not convinced that "Bela" will be the solution for me. He's thinking that early withdrawal from Prograf (meaning they drop me down to 1 mg Bid quickly) will give me enough protection from rejection while not inducing the nephrotoxic side effects that accompany higher doses. That dichotomy is hard to wrap my head around; I need the drugs to stop rejection, but the drugs are toxic to the kidney.